重卡驱动桥壳疲劳稳健性与轻量化设计

驱动桥壳轻量化设计对于提高承载能力、降低生产成本具有重要的意义.本文在驱动桥壳有限元分析和疲劳分析计算的基础上建立驱动桥壳多目标优化模型，对重型卡车驱动桥壳进行参数化设计，建立正交试验表，利用田口方法和综合评价方法对驱动桥壳的疲劳性能稳健性和质量进行优化设计.优化结果表明，此方法可以应用于驱动桥壳的多目标优化，优化后驱动桥壳的疲劳稳健性能得到提高，减轻了质量，因此节约了桥壳材料，降低了生产和运营成本，提高了设计水平.     

Geochemistry of Clayey Aquitard Pore Water as Archive of Paleo-Environment,Western Bohai Bay

The record of paleo-environment in clayey aquitard pore water is much more effective relative to aquifer groundwater owing to the low permeability of clayey aquitard. Oxygen-18 (18O), deuterium (D), an...     

Optimal investment problem for an insurer and a reinsurer

This paper studies the optimal investment problem for an insurer and a reinsurer. The basic claim process is assumed to follow a Brownian motion with drift and the insurer can purchase proportional reinsurance from the reinsurer. The insurer and the reinsurer are allowed to invest in a risk-free asset and a risky asset. Moreover, the authors consider the correlation between the claim process and the price process of the risky asset. The authors ?rst study the optimization problem of maximizing the expected exponential utility of terminal wealth for the insurer. Then with the optimal reinsurance strategy chosen by the insurer, the authors consider two optimization problems for the reinsurer: The problem of maximizing the expected exponential utility of terminal wealth and the problem of minimizing the ruin probability. By solving the corresponding Hamilton-Jacobi-Bellman equations, the authors derive the optimal reinsurance and investment strategies, explicitly. Finally, the authors illustrate the equality of the reinsurer's optimal investment strategies under the two cases.     

Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets

Introduction

Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets and carried out in vitro islet hormone secretion studies to provide functional confirmation for the species-specific role of peptide YY (PYY) in mouse islets.

Materials and methods

GPCR peptide ligand mRNAs in human and mouse islets were quantified by quantitative real-time PCR relative to the reference genes ACTB, GAPDH, PPIA, TBP and TFRC. The pathways connecting GPCR peptide ligands with their receptors were identified by manual searches in the PubMed, IUPHAR and Ingenuity databases. Distribution of PYY protein in mouse and human islets was determined by immunohistochemistry. Insulin, glucagon and somatostatin secretion from islets was measured by radioimmunoassay.

Results

We have quantified GPCR peptide ligand mRNA expression in human and mouse islets and created specific signalomes mapping the pathways by which islet peptide ligands regulate human and mouse GPCR signalling. We also identified species-specific islet expression of several GPCR ligands. In particular, PYY mRNA levels were ~ 40,000-fold higher in mouse than human islets, suggesting a more important role of locally secreted Pyy in mouse islets. This was confirmed by IHC and functional experiments measuring insulin, glucagon and somatostatin secretion.

Discussion

The detailed human and mouse islet GPCR peptide ligand atlases will allow accurate translation of mouse islet functional studies for the identification of GPCR/peptide signalling pathways relevant for human physiology, which may lead to novel treatment modalities of diabetes and metabolic disease.

     

Synthesis and Largely Enhanced Nonlinear Refraction of Au@Cu_2O Core-Shell Nanorods

Au@Cu_2O core-shell nanorods with tunable thickness of Cu_2O shell were synthesized and their linear and nonlinear optical responses were investigated. Two transverse plasmon resonance peaks were observed when the Au nanorods were coated with Cu_2O shells, which were adjusted by the Cu_2O shell thickness. The nonlinear absorption of the Au@Cu_2O nanorods is enhanced by 5 times at the longitudinal plasmon resonance wavelength compared with that of bare Au nanorods. More intriguingly, largely enhanced nonlinear refraction and suppressed nonlinear absorption at the transverse plasmon resonance wavelength were observed in the Au@Cu_2O nanorods. Our findings indicate the existence of strong local field enhancement at the interface between the Au core and the Cu_2O shell, which would provide a promising strategy in designing plasmonic nonlinear nanodevices with good nonlinear figures of merit.     

Effects of Strain Rate,Temperature and Grain Size on the Mechanical Properties and Microstructure Evolutions of Polycrystalline Nickel Nanowires: A Molecular Dynamics Simulation

Through molecular dynamics(MD)simulation,the dependencies of temperature,grain size and strain rate on the mechanical properties were studied.The simulation results demonstrated that the strain rate from 0.05 to 2 ns~(–1 )affected the Young’s modulus of nickel nanowires slightly,whereas the yield stress increased.The Young’s modulus decreased approximately linearly;however,the yield stress firstly increased and subsequently dropped as the temperature increased.The Young’s modulus and yield stress increased as the mean grain size increased from 2.66 to6.72 nm.Moreover,certain efforts have been made in the microstructure evolution with mechanical properties association under uniaxial tension.Certain phenomena such as the formation of twin structures,which were found in nanowires with larger grain size at higher strain rate and lower temperature,as well as the movement of grain boundaries and dislocation,were detected and discussed in detail.The results demonstrated that the plastic deformation was mainly accommodated by the motion of grain boundaries for smaller grain size.However,for larger grain size,the formations of stacking faults and twins were the main mechanisms of plastic deformation in the polycrystalline nickel nanowire.     

基于NOMA的认知无线电网络功率分配

考虑采用非正交多址接入(NOMA)技术的认知无线电网络下行链路的功率分配问题,旨在最大化接入系统的次用户数,提升系统的频谱效率.在不影响主用户通信的情况下,对次用户进行合理的功率分配,使得系统接入的次用户数最大化.在系统可用功率未得到充分利用时,考虑在接入系统的次用户间对未利用的功率再次进行功率分配,提升系统的频谱效率.仿真结果显示:当次用户最小速率为2.5 bit·s~(-1),请求接入系统的次用户数为10时,频谱效率可提升13%.     

Fuzzy Views on Black-Litterman Portfolio Selection Model

In this paper, views of investor are described in fuzzy sets, and two fuzzy Black-Litterman models are constructed with fuzzy views and fuzzy random views respectively. In the models, expected returns and uncertainty matrix of views are redefined and the views are formulated by fuzzy approaches suitably. Then the models are tested with data from Chinese financial markets. Empirical results show that the fuzzy random views model performs the best, and both the fuzzy models are better than the traditional ones, demonstrating that the fuzzy approaches can contain more information in the views and measure the uncertainty more correctly.     

De Casteljau Algorithm and Degree Elevation of Toric Surface Patches

De Casteljau algorithm and degree elevation of Bézier and NURBS curves/surfaces are two important techniques in computer aided geometric design. This paper presents the de Casteljau algorithm and degree elevation of toric surface patches, which include tensor product and triangular rational Bézier surfaces as special cases. Some representative examples of toric surface patches with common shapes are illustrated to verify these two algorithms. Moreover, the authors also apply the degree elevation of toric surface patches to isogeometric analysis. And two more examples show the effectiveness of proposed method.     

人类卫生健康共同体视域下的全球科技合作研究——以新冠肺炎疫情为背景

新冠疫情暴发以来,中国政府和人民秉持人类命运共同体理念,运用一系列先进技术,在较短时间内扭转了国内疫情的严峻形势.在此背景下,为了更好地发挥中国方案在全球抗疫中的作用,文章运用内容分析法和归纳分析法,首先梳理了从人类命运共同体到人类卫生健康共同体的理论逻辑,其次探究了人类卫生健康共同体、全球科技合作与疫情防控之间的结构关系,最后分析了中国疫情防控的有效举措,进而得出结论:中国疫情防控工作的成效离不开人类命运共同体理念的指引和全球科技合作的开展,而中国在平台建设、机制整合及合作网络等领域的方案共享将有助于遏制全球疫情的蔓延.